実績内容
外来受診月平均延べ患者数は500～600名/月であり、低身長や思春期が早い・遅いなどの成長に関する主訴が最も多い。入院の月平均延べ患者数は80名/月ほどであり、下垂体、副腎、性腺系の評価のための負荷試験入院が主体である。
内分泌疾患の中でも、下垂体機能低下症、性分化疾患、副腎疾患、骨系統疾患などが多いのが当科の特徴である。
誌上発表
Improvement of Fibrous Dysplasia After Burosumab Therapy in a Pediatric Patient with McCune-Albright Syndrome: A Case Report.
Sawamura K, Hamajima T, Kitoh H.
JBJS Case Connect. 2024 Sep 20;14(3). doi: 10.2106/JBJS.CC.24.00279. PMID: 39303050.
Incidence and Risk Factors for Adrenal Crisis in Pediatric-onset Adrenal Insufficiency: A Prospective Study.
Hosokawa M, Ichihashi Y, Sato Y, Shibata N, Nagasaki K, Ikegawa K, Hasegawa Y, Hamajima T, Nagamatsu F, Suzuki S, Numakura C, Amano N, Sasaki G, Nagahara K, Soneda S, Ariyasu D, Maeda M, Kamasaki H, Aso K, Hasegawa T, Ishii T.
J Clin Endocrinol Metab. 2024 Jul 12;109(8):e1602-e1607. doi:10.1210/clinem/dgad753. PMID: 38128002.
Nagasaki K. Clinical and molecular analyses of isolated central congenital
hypothyroidism based on a survey conducted in Japan.
Shibata N, Numakura C, Hamajima T, Miyako K, Fujiwara I, Mori J, Saitoh A, Nagasaki K.
Endocr J. 2024 May 23;71(5):471-480. doi: 10.1507/endocrj.EJ23-0391. Epub 2024 Mar 8. PMID:
38462462.
Clinical outcomes and medical management of achondroplasia in Japanese children: A retrospective medical record review of clinical data. Am J Med Genet A.
Saitou H, Kitaoka T, Kubota T, Kanno J, Mochizuki H, Michigami T, Hasegawa K, Fujiwara I, Hamajima T, Harada D, Seki Y, Nagasaki K, Dateki S, Namba N, Tokuoka H, Pimenta JM, Cohen S, Ozono K.
2024 Aug;194(8):e63612. doi: 10.1002/ajmg.a.63612. Epub 2024 Mar 30. PMID: 38554024.
DHX37 Variant is One of Common Genetic Causes in Japanese Patients with Testicular Regression Syndrome / Partial Gonadal Dysgenesis without Müllerian Derivatives. Horm Res Paediatr.
Shimura K, Ichihashi Y, Nakano S, Sato T, Hamajima T, Numasawa K, Narumi S, Hasegawa T, Ishii T.
Horm Res Paediatr. 2024 Feb 15. doi: 10.1159/000537761. Epub ahead of print. PMID: 38359811.
Changes of the lower limb deformity in children with FGF23-related hypophosphatemic rickets treated with Burosumab: a single-center prospective study. J Pediatr Orthop B.
Sawamura K, Hamajima T, Izawa M, Kaneko H, Kitamura A, Kitoh H.
J Pediatr Orthop B. 2024 Jan 1;33(1):90-96. doi: 10.1097/BPB.0000000000001054. Epub 2022 Dec 26.
PMID: 36728857.
A case of hyperphosphatemic familial tumoral calcinosis due to maternal uniparental disomy of a GALNT3 variant.
Nishimura-Kinoshita N, Ohata Y, Sawai H, Izawa M, Takeyari S, Kubota T, Omae Y, Ozono K, Tokunaga K, Hamajima T.
Clin Pediatr Endocrinol. 2023;32(3):161-167. doi: 10.1297/cpe.2022-0071. Epub 2023 Apr 14. PMID: 37362161; PMCID: PMC10288290.
Transport and Golgi organization 2 deficiency with a prominent elevation of C14:1 during a metabolic crisis: A case report.
Yokoi K, Nakajima Y, Takahashi Y, Hamajima T, Tajima G, Saito K, Miyai S, Inagaki H, Yoshikawa T, Kurahashi H, Ito T.
JIMD Rep. 2022 Oct 27;64(1):3-9. doi: 10.1002/jmd2.12275. PMID: 36636595; PMCID: PMC9830013.
Various phenotypes of short stature with heterozygous IGF-1 receptor (IGF1R) mutations.
Kawashima-Sonoyama Y, Hotsubo T, Hamajima T, Hamajima N, Fujimoto M, Namba N, Kanzaki S.
Clin Pediatr Endocrinol.
2022;31(2):59-67. doi: 10.1297/cpe.2021-0064. Epub 2022 Feb 7. PMID: 35431446; PMCID: PMC8981046.
First Morning Pregnanetriol and 17-Hydroxyprogesterone Correlated Significantly in 21-Hydroxylase Deficiency.
Itonaga T, Izawa M, Hamajima T, Hasegawa Y.
Front Endocrinol (Lausanne). 2022 Jan 24;12:808254. doi: 10.3389/fendo.2021.808254. PMID: 35140686; PMCID: PMC8820395.
Complete androgen insensitivity syndrome with accelerated onset of puberty due to a Sertoli cell tumor.
Izawa M, Hisamatsu E, Yoshino K, Yoshida M, Sato T, Narumi S, Hasegawa T, Hamajima T.
Clin Pediatr Endocrinol. 2021;30(2):99-104. doi: 10.1297/cpe.30.99. Epub 2021 Apr 3. PMID: 33867670; PMCID: PMC8022032.
Clinical Features of 57 Patients with Lipoid Congenital Adrenal Hyperplasia: Criteria for Nonclassic Form Revisited.
Ishii T, Tajima T, Kashimada K, Mukai T, Tanahashi Y, Katsumata N, Kanno J, Hamajima T, Miyako K, Ida S, Hasegawa T.
J Clin Endocrinol Metab. 2020 Nov 1;105(11):dgaa557. doi: 10.1210/clinem/dgaa557. PMID: 32835366.
