実績内容
主な診療実績（2024年10月時点）
| 維持腹膜透析患者数 | 9人 |
| 腎移植後患者通院数 | 21人 |
| 当センターでの腎移植総数 | 30人 |
| 経皮的針腎生検 | 約60件／年 |
| 新規難治性ネフローゼ症候群 | 約10人／年 |
誌上発表
Ravulizumab in Atypical Hemolytic Uremic Syndrome: An Analysis of 2-Year Efficacy and Safety Outcomes in 2 Phase 3 Trials.
Dixon BP, Kavanagh D, Aris ADM, Adams B, Kang HG, Wang E, Garlo K, Ogawa M, Amancha P, Chakravarty S, Heyne N, Kim SH, Cataland S, Yoon SS, Miyakawa Y, Luque Y, Muff-Luett M, Tanaka K, Greenbaum LA.
Kidney Med. 2024 Jun 14;6(8):100855. doi: 10.1016/j.xkme.2024.100855. eCollection 2024 Aug.
Sodium removal per ultrafiltration volume in automated peritoneal dialysis in pediatric patients.
Tokunaga T, Hamada R, Inoguchi T, Terano C, Mikami N, Harada R, Hamasaki Y, Ishikura K, Hataya H, Honda M.
Pediatr Nephrol. 2024 Sep;39(9):2753-2758. doi: 10.1007/s00467-024-06383-9. Epub 2024 May 2.
Simple and practical formulas for stage 1 hypertension reference values in children.
Shirane S, Honda M, Hamada R, Uemura O, Fujita N, Gotoh Y.
Acta Paediatr. 2024 Jun;113(6):1373-1375. doi: 10.1111/apa.17226. Epub 2024 Mar 28.
Reference blood pressure values obtained using the auscultation method for 2-year-old Japanese children: from the Japan Environment and Children’s Study.
Fujita N, Mezawa H, Pak K, Uemura O, Yamamoto-Hanada K, Sato M, Saito-Abe M, Miyaji Y, Yang L, Nishizato M, Ohya Y, Ishikura K, Hamasaki Y, Sakai T, Yamamoto K, Ito S, Honda M, Gotoh Y; Japan Environment, Children’s Study Group.
Clin Exp Nephrol. 2023 Oct;27(10):857-864. doi: 10.1007/s10157-023-02370-w. Epub 2023 Jun 30.
Analysis of the ratio of urinary beta-2-microglobulin to total protein concentration in children with isolated tubulointerstitial disease.
Nishimura T, Uemura O, Hibino S, Tanaka K, Iwata N, Yamamoto M, Matsukuma E, Miyake Y, Gotoh Y, Fujita N.
Clin Exp Nephrol. 2023 Aug;27(8):701-706. doi: 10.1007/s10157-023-02349-7. Epub 2023 Apr 24.
Eculizumab for paediatric patients with atypical haemolytic uraemic syndrome: full dataset analysis of post-marketing surveillance in Japan.
Ito S, Hataya H, Ashida A, Hamada R, Ishikawa T, Ishikawa Y, Shimono A, Konomoto T, Miyazawa T, Ogura M, Tanaka K, Kagami S.
Nephrol Dial Transplant. 2023 Feb 13;38(2):414-424. doi: 10.1093/ndt/gfac150.
Urinary extracellular vesicles signature for diagnosis of kidney disease.
Takizawa K, Ueda K, Sekiguchi M, Nakano E, Nishimura T, Kajiho Y, Kanda S, Miura K, Hattori M, Hashimoto J, Hamasaki Y, Hisano M, Omori T, Okamoto T, Kitayama H, Fujita N, Kuramochi H, Ichiki T, Oka A, Harita Y.
iScience. 2022 Nov 8;25(11):105416. doi: 10.1016/j.isci.2022.105416. eCollection 2022 Nov 18.
Early predictive factors for progression to kidney failure in infants with severe congenital anomalies of the kidney and urinary tract.
Nishi K, Uemura O, Harada R, Yamamoto M, Okuda Y, Miura K, Gotoh Y, Kise T, Hirano D, Hamasaki Y, Fujita N, Uchimura T, Ninchoji T, Isayama T, Hamada R, Kamei K, Kaneko T, Ishikura K; Pediatric CKD Study Group in Japan in conjunction with the Committee of Measures for Pediatric CKD of the Japanese Society of Pediatric Nephrology.
Pediatr Nephrol. 2023 Apr;38(4):1057-1066. doi: 10.1007/s00467-022-05703-1. Epub 2022 Aug 11.
Ultrasonographic reference values and a simple yet practical formula for estimating average kidney length in Japanese children.
Fujita N, Uemura O, Harada R, Matsumura C, Sakai T, Hamasaki Y, Kamei K, Nishi K, Kaneko T, Ishikura K, Gotoh Y; the Pediatric CKD Study Group in Japan in conjunction with the Committee of Measures for Pediatric CKD of the Japanese Society of Pediatric Nephrology.
Clin Exp Nephrol. 2022 Aug;26(8):808-818. doi: 10.1007/s10157-022-02205-0. Epub 2022 Apr 16.
Validation of the estimated glomerular filtration rate equation for Japanese children younger than 2 years.
Gotoh Y, Uemura O, Fujita N, Hamasaki Y, Honda M, Ishikura K; Pediatric CKD Study Group in Japan in conjunction with the Committee of Measures for Pediatric CKD of the Japanese Society of Pediatric Nephrology.
Clin Exp Nephrol. 2022 Mar;26(3):266-271. doi: 10.1007/s10157-021-02165-x. Epub 2022 Jan 1.
Mycophenolate Mofetil after Rituximab for Childhood-Onset Complicated Frequently-Relapsing or Steroid-Dependent Nephrotic Syndrome.
Iijima K, Sako M, Oba M, Tanaka S, Hamada R, Sakai T, Ohwada Y, Ninchoji T, Yamamura T, Machida H, Shima Y, Tanaka R, Kaito H, Araki Y, Morohashi T, Kumagai N, Gotoh Y, Ikezumi Y, Kubota T, Kamei K, Fujita N, Ohtsuka Y, Okamoto T, Yamada T, Tanaka E, Shimizu M, Horinochi T, Konishi A, Omori T, Nakanishi K, Ishikura K, Ito S, Nakamura H, Nozu K; Japanese Study Group of Kidney Disease in Children.
J Am Soc Nephrol. 2022 Feb;33(2):401-419. doi: 10.1681/ASN.2021050643. Epub 2021 Dec 8.
Serum albumin level is associated with mycophenolic acid concentration in children with idiopathic nephrotic syndrome.
Nishimura T, Uemura O, Hibino S, Tanaka K, Kitagata R, Yuzawa S, Kasagi T, Fujita N.
Eur J Pediatr. 2022 Mar;181(3):1159-1165. doi: 10.1007/s00431-021-04294-7. Epub 2021 Nov 15.
Mortality outcomes and clinical background of children on maintenance dialysis without receiving kidney transplantation.
Hibino S, Kitagata R, Nishimura T, Kagata K, Tanaka K, Fujita N.
Clin Exp Nephrol. 2022 Feb;26(2):198-204. doi: 10.1007/s10157-021-02132-6. Epub 2021 Oct 11.
Comparison of inulin clearance with 2-h creatinine clearance in Japanese pediatric patients with renal disease: open-label phase 3 study of inulin.
Uemura O, Ishikura K, Kamei K, Hamada R, Yamamoto M, Gotoh Y, Fujita N, Sakai T, Sano T, Fushimi M, Iijima K.
Clin Exp Nephrol. 2022 Feb;26(2):132-139. doi: 10.1007/s10157-021-02133-5. Epub 2021 Sep 25.
Genotype-Phenotype Correlation in WT1 Exon 8 to 9 Missense Variants.
Nagano C, Takaoka Y, Kamei K, Hamada R, Ichikawa D, Tanaka K, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Okada E, Horinouchi T, Yamamura T, Tsuji Y, Noguchi Y, Ishimori S, Nagase H, Ninchoji T, Iijima K, Nozu K.
Kidney Int Rep. 2021 May 19;6(8):2114-2121. doi: 10.1016/j.ekir.2021.05.009. eCollection 2021 Aug.
Response to steroid and immunosuppressive therapies may predict post-transplant recurrence of steroid-resistant nephrotic syndrome.
Miura K, Ando T, Kanda S, Hashimoto T, Kaneko N, Ishizuka K, Hamada R, Hataya H, Hotta K, Gotoh Y, Nishiyama K, Hamasaki Y, Shishido S, Fujita N, Hattori M.
Pediatr Transplant. 2022 Dec;26(8):e14103. doi: 10.1111/petr.14103. Epub 2021 Jul 26.
Distribution of serum adiponectin isoforms in pediatric patients with steroid-sensitive nephrotic syndrome.
Tamai T, Kamijo K, Abe Y, Hibino S, Sakurai S, Watanabe S, Watanabe Y, Nimura S, Shiratori A, Takayanagi T, Watanabe T, Nakano Y, Ikeda H, Dobashi K, Nakano Y, Mizuno K, Itabashi K.
Clin Exp Nephrol. 2021 Sep;25(9):1027-1034. doi: 10.1007/s10157-021-02085-w. Epub 2021 Jun 1.
Perinatal factors contributing to chronic kidney disease in a cohort of Japanese children with very low birth weight.
Uemura O, Ishikura K, Kaneko T, Hirano D, Hamasaki Y, Ogura M, Mikami N, Gotoh Y, Sahashi T, Fujita N, Yamamoto M, Hibino S, Nakano M, Wakano Y, Honda M.
Pediatr Nephrol. 2021 Apr;36(4):953-960. doi: 10.1007/s00467-020-04791-1. Epub 2020 Oct 17.
The long-acting C5 inhibitor, ravulizumab, is efficacious and safe in pediatric patients with atypical hemolytic uremic syndrome previously treated with eculizumab.
Tanaka K, Adams B, Aris AM, Fujita N, Ogawa M, Ortiz S, Vallee M, Greenbaum LA.
Pediatr Nephrol. 2021 Apr;36(4):889-898. doi: 10.1007/s00467-020-04774-2. Epub 2020 Oct 13.
Management of a Preterm Infant with Renal Tubular Dysgenesis: A Case Report and Review of the Literature.
Kondoh T, Kawai Y, Matsumoto Y, Kumagai N, Miyata M, Tanaka K, Hibino S, Fujita N, Ikezumi Y.
Tohoku J Exp Med. 2020 Sep;252(1):9-14. doi: 10.1620/tjem.252.9.
Kidney function of Japanese children undergoing kidney transplant with preemptive therapy for cytomegalovirus infection.
Gotoh Y, Shishido S, Hamasaki Y, Watarai Y, Hattori M, Miura K, Ishizuka K, Fujita N, Saito K, Nakagawa Y, Hotta K, Hataya H, Hamada R, Sato H, Kitayama H, Ishikura K, Honda M, Uemura O.
Transpl Infect Dis. 2020 Jun;22(3):e13271. doi: 10.1111/tid.13271. Epub 2020 Mar 11.
Prophylactic amoxicillin for the prevention of meningococcal infection in infants with atypical hemolytic uremic syndrome under treatment with eculizumab: a report of two cases.
Tanaka K, Fujita N, Hibino S.
CEN Case Rep. 2020 Aug;9(3):247-251. doi: 10.1007/s13730-020-00465-x. Epub 2020 Apr 2.
Medullary Cystic Kidney Disease and Focal Segmental Glomerulosclerosis Caused by a Compound Heterozygous Mutation in TTC21B.
Hibino S, Morisada N, Takeda A, Tanaka K, Nozu K, Yamakawa S, Iijima K, Fujita N.
Intern Med. 2020 Jul 15;59(14):1735-1738. doi: 10.2169/internalmedicine.4266-19. Epub 2020 Apr 2.
Steroid- and immunosuppressant-based protocol of Henoch-Schönlein purpura nephritis without angiotensin inhibitors in the acute phase.
Kasahara K, Gotoh Y, Kuroyanagi Y, Nagano C, Yamakawa S, Tanaka K, Takeda A, Uemura O.
Minerva Pediatr (Torino). 2023 Apr;75(2):201-209. doi: 10.23736/S2724-5276.18.05324-0. Epub 2018 Nov 7.
Solute Clearance and Fluid Removal: Large-Dose Cyclic Tidal Peritoneal Dialysis.
Hibino S, Uemura O, Uchida H, Majima H, Yamaguchi R, Tanaka K, Kawaguchi A, Yamakawa S, Fujita N.
Ther Apher Dial. 2019 Apr;23(2):180-186. doi: 10.1111/1744-9987.12765. Epub 2018 Oct 24.
A review of clinical characteristics and genetic backgrounds in Alport syndrome.
Nozu K, Nakanishi K, Abe Y, Udagawa T, Okada S, Okamoto T, Kaito H, Kanemoto K, Kobayashi A, Tanaka E, Tanaka K, Hama T, Fujimaru R, Miwa S, Yamamura T, Yamamura N, Horinouchi T, Minamikawa S, Nagata M, Iijima K.
Clin Mol Allergy. 2021 Aug 2;19(1):13. doi: 10.1007/s10157-018-1629-4. Epub 2018 Aug 20.
Creatinine-based equation to estimate the glomerular filtration rate in Japanese children and adolescents with chronic kidney disease.
Uemura O, Nagai T, Ishikura K, Ito S, Hataya H, Gotoh Y, Fujita N, Akioka Y, Kaneko T, Honda M.
Clin Exp Nephrol. 2014 Aug;18(4):626-33. doi: 10.1007/s10157-013-0856-y. Epub 2013 Sep 7.
Is the new Schwartz equation derived from serum creatinine and body length suitable for evaluation of renal function in Japanese children?
Uemura O, Honda M, Matsuyama T, Ishikura K, Hataya H, Nagai T, Ikezumi Y, Fujita N, Ito S, Iijima K; Japanese Society for Pediatric Nephrology, the Committee of Measures for Pediatric CKD.
Eur J Pediatr. 2012 Sep;171(9):1401-4. doi: 10.1007/s00431-012-1772-y. Epub 2012 Jun 20.
Age, gender, and body length effects on reference serum creatinine levels determined by an enzymatic method in Japanese children: a multicenter study.
Uemura O, Honda M, Matsuyama T, Ishikura K, Hataya H, Yata N, Nagai T, Ikezumi Y, Fujita N, Ito S, Iijima K, Kitagawa T.
Clin Exp Nephrol. 2011 Oct;15(5):694-699. doi: 10.1007/s10157-011-0452-y. Epub 2011 Apr 21.
清潔間欠導尿を要する二分脊椎患児における腎障害発生のリスク因子の検討.
西村 竜哉, 日比野 聡, 田中 一樹, 北形 綾一, 湯澤 壮太郎, 藤田 直也.
日本小児腎臓病学会雑誌. 35: 19-26; 2022
固有腎の尿量が良好な腎移植例では移植尿管の狭窄に注意が必要である.
野末 圭祐, 田中 一樹, 松林 広樹, 服部 俊彦, 笠置 俊希, 藤浦 直子, 山口 玲子, 寺野 千香子, 日比野 聡, 小林 孝彰, 藤田 直也.
日本小児腎不全学会雑誌. 42: 194-197; 2022
男性Alport症候群の病期による推算糸球体濾過量の低下速度の変化.
服部 俊彦, 日比野 聡, 松林 広樹, 藤浦 直子, 野末 圭祐, 笠置 俊希, 寺野 千香子, 山口 玲子, 田中 一樹, 藤田 直也.
日本小児腎不全学会雑誌. 42: 89-92; 2022
aHUS 症例における抗補体 C5 阻害薬治療の長期経過─エクリズマブからラブリズマブへの切り替症例の報告─.
田中 一樹.
日本小児腎不全学会誌. 42: 60-64; 2022
内科的治療で管理可能であった嫌気性菌による腹膜透析カテーテル皮下トンネル感染の一例.
笠置 俊希, 松林 広樹, 野末 圭祐, 服部 俊彦, 藤浦 直子, 寺野 千香子, 山口 玲子, 田中 一樹, 日比野 聡, 藤田 直也.
日本小児PD・HD研究会雑誌. 33: 47-50; 2022
乳幼児の腹膜透析 透析メニューについて.
日比野 聡, 松林 広樹, 藤浦 直子, 野末 圭祐, 服部 俊彦, 笠置 俊希, 寺野 千香子, 山口 玲子, 田中 一樹, 藤田 直也.
日本小児PD・HD研究会雑誌. 33: 16-23; 2022
急性胃腸炎の経過中にタクロリムスの血中濃度の異常高値を認めた生体腎移植後の女児例.
笠置 俊希, 湯澤 壮太郎, 北形 綾一, 西村 竜哉, 田中 一樹, 日比野 聡, 藤田 直也.
日本小児腎不全学会雑誌. 41: 58-62; 2021
乳幼児腹膜透析症例の嘔吐・哺乳不良と栄養方法.
湯澤 壮太郎, 笠置 俊希, 北形 綾一, 西村 竜哉, 田中 一樹, 日比野 聡, 藤田 直也.
日本小児腎不全学会雑誌. 40: 116-120; 2020
先天性水腎症の増悪に伴い高レニン性高血圧を発症した男児例.
北形 綾一, 笠置 俊希, 湯澤 壮太郎, 西村 竜哉, 田中 一樹, 日比野 聡, 藤田 直也, 久松 英治, 吉野 薫.
日本小児高血圧研究会誌. 17: 13-17; 2020
新生児期に一過性の低カリウム血症を認めた一例.
西村 竜哉, 澤田 なおみ, 神澤 孝洋, 笠置 俊希, 湯澤 壮太郎, 北形 綾一, 田中 一樹, 日比野 聡, 加藤 英子, 家田 訓子, 藤田 直也.
日本小児体液研究会誌. 12: 41-45; 2020
小児腎疾患患者に対する24時間自動血圧測定の有用性.
内田 博之, 北形 綾一, 西村 竜哉, 加賀田 敬郎, 田中 一樹, 日比野 聡, 藤田 直也.
日本小児高血圧研究会誌. 16: 9-13; 2019
初回腎生検で膜性増殖性糸球体腎炎Ⅲ型を呈し、WT1遺伝子exon9領域に新規ミスセンス異変を同定した女児例.
北方 綾一, 西村 竜哉, 加賀田 敬郎, 内田 博之, 田中 一樹, 日比野 聡, 長野 那智, 野津 寛大, 飯島 一誠, 武田 朝美, 藤田 直也.
日本小児腎不全学会雑誌 39: 172-175; 2019
小児ネフローゼ症候群におけるシクロスポリンの液剤とカプセル剤の薬物動態の変化.
伊藤 創太郎, 山川 聡, 日比野 聡, 河口 亜津彩, 山口 怜子, 真島 久和, 内田 博之, 藤田 直也.
日本小児腎臓病学会雑誌 32: 24-30; 2019
多剤併用療法前にステロイドパルス療法を施工した小児IgA腎症の腎予後に関する検討.
山田 拓司, 藤田 直也, 山川 聡, 後藤 芳充, 牛嶌 克実, 金原 有里, 上村 治.
日本小児腎臓病学会雑誌 32: 16-23; 2019
ネフローゼ症候群の体液貯留時におけるトルバプタンの利尿効果.
日比野 聡, 北方 綾一, 西村 竜哉, 加賀田 敬郎, 内田 博之, 田中 一樹, 藤田 直也.
日本小児体液研究会誌 11: 61-66; 2019
